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Antigenic Specificity | UHRF1BP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 17 amino acid peptide near the center of human UHRF1BP1. |
Other Names | [Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1, ICBP90-binding protein 1, UHRF1 binding protein 1] |
Gene, Accession # | [UHRF1BP1], Gene ID: 54887, NCBI: NP_060224 |
Catalog # | MBS9402878 |
Price | $320 |
Order / More Info | UHRF1BP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |