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Antigenic Specificity | PI3KCA (Center), 504-533 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PI3KCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 504-533 amino acids from the Central region of human PI3KCA. Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. |
Immunogen | n/a |
Other Names | [Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; PI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide-3-kinase catalytic alpha polypeptide; Serine/threonine protein kinase PIK3CA; PIK3CA] |
Gene, Accession # | [PIK3CA], Gene ID: 5290, NCBI: NP_006209.2, UniProt: P42336 |
Catalog # | MBS9211098 |
Price | $165, $370 |
Order / More Info | PI3KCA (Center), 504-533 Antibody from MYBIOSOURCE INC. |
Product Specific References | Tiwari, S. Nat Immunol. August; 10(8): 907-17 (2009). Ballou, L.M., et al., J. Biol. Chem. 278(26):23472-23479 (2003). Singh, B., et al., Genes Dev. 16(8):984-993 (2002). Shayesteh, L., et al., Nat. Genet. 21(1):99-102 (1999). Volinia, S., et al., Genomics 24(3):472-477 (1994). Hiles, I.D., et al., Cell 70(3):419-429 (1992). |