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Antigenic Specificity | CARD14 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acts as a scaffolding protein that can activate the inflammatory transcription factor NF-kappa-B and p38/JNK MAP kinase signaling pathways. Forms a signaling complex with BCL10 and MALT1, and activates MALT1 proteolytic activity and inflammatory gene expression. MALT1 is indispensable for CARD14-induced activation of NF-kappa-B and p38/JNK MAP kinases (PubMed:11278692, PubMed:21302310, PubMed:27113748, PubMed:27071417). May play a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis. |
Immunogen | Immunogen: Recombinant funsion protein containing a sequence corresponding to amino acids 200-500 of human CARD14 (NP 001244899.1). |
Other Names | [PRP; PSS1; BIMP2; CARMA2; PSORS2] |
Gene, Accession # | [CARD14], Gene ID: 79092, NCBI: NP_001244899.1, UniProt: Q9BXL6 |
Catalog # | MBS8550399 |
Price | $280 |
Order / More Info | CARD14 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |