Edit |   |
---|---|
Antigenic Specificity | JUN |
Clone | [1G6B11] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | JUN is also named as c-Jun and AP1, belongs to the bZIP family and Jun subfamily. JUN, the most extensively studied protein of the activator protein-1 (AP-1) complex, is involved in numerous cell activities, such as proliferation, apoptosis, survival, tumorigenesis and tissue morphogenesis. JUN is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. JUN is a basic leucine zipper (bZIP) transcription factor that acts as homo- or heterodimer, binding to DNA and regulating gene transcription. In additon, extracellular signals can induce post-translati |
Immunogen | Immunogen: Fusion Protein of JUN Buffer: PBS with 0.02% sodium azide, 50% glycerol, PH7.3 Conjugation: Unconjugated |
Other Names | [Activator protein 1; AP 1; AP1; c Jun; JUN; jun oncogene; P39; Proto oncogene c Jun; Transcription factor AP 1] |
Gene, Accession # | [JUN], Gene ID: 3725, NCBI: BC068522, UniProt: P05412 |
Catalog # | MBS2549091 |
Price | $220, $290, $435 |
Order / More Info | JUN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |