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Antigenic Specificity | TEM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least two isoforms of TEM1 are known to exist; this antibody recognizes only the larger isoform. TEM1 Antibody: Tumor endothelial marker (TEM) 1 was originally identified as a human embryonic fibroblast-specific antigen and was later determined to be endosialin, a single-pass transmembrane glycoprotein that has multiple extracellular domains, including three EGF-like domains, a sushi-like domain, and a C lectin-like domain. TEM proteins are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. While TEM1 is not required for angiogenesis during fetal development, postnatal growth or wound healing, it plays a role in tumor growth, invasion, and metastasis. Fibronect |
Immunogen | Immunogen: TEM1 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of the human TEM1. Buffer: TEM1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [TEM1; TEM1; CD164L1; TEM1; Endosialin; Tumor endothelial marker 1; CD248 molecule, endosialin], [CD248; CD248; TEM1; CD164L1; CD164L1; TEM1] |
Gene, Accession # | [CD248], Gene ID: 57124, NCBI: NP_065137, UniProt: Q9HCU0 |
Catalog # | MBS150946 |
Price | $375 |
Order / More Info | TEM1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |