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Antigenic Specificity | TIP47 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TIP47 Antibody: Tail-interacting protein (TIP47) is a cytosolic protein essential for the transport of mannose-6-phosphate receptors (MPRs) from endosomes to the trans-Golgi compartments in cells. TIP47 is recruited from the cytoplasm to the late endosomal surface by the Ras-associated protein Rab9 GTPase, enabling it to bind more efficiently to MPR cytoplasmic domains. Recently, it was shown that TIP47 regulates the expression of Rab9, as expression of siRNA to TIP47 in transfected cells dramatically decreased the half-life of the Rab9 protein in addition to stabilizing the subcellular localization of Rab9. At least two isoforms of TIP47 are known to exist. |
Immunogen | Immunogen: TIP47 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human TIP47. Buffer: TIP47 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [TIP47; PP17; TIP47; M6PRBP1; Perilipin-3; 47 kDa mannose 6-phosphate receptor-binding protein; 47 kDa MPR-binding protein; mannose-6-phosphate receptor binding protein 1], [PLIN3; PLIN3; PP17; TIP47; M6PRBP1; M6PRBP1; TIP47; 47 kDa MPR-binding protein; PP17] |
Gene, Accession # | [M6PRBP1], Gene ID: 10226, NCBI: O60664.2, UniProt: O60664 |
Catalog # | MBS151454 |
Price | $375 |
Order / More Info | TIP47 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |