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Antigenic Specificity | TRIP6 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TRIP6 antibody detects endogenous levels of total TRIP6. Description: This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.Function: Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphat |
Immunogen | Immunogen: Purified recombinant fragment of human TRIP6 expressed in E. Coli Subcellular Location: Cytoplasm > Cytoskeleton. Cell Junction > Focal Adhesion. Nucleus. Cytoplasm. Shuttles between nucleus and cytoplasm. Tissue Specificity: Abundantly expressed in kidney, liver and lung. Lower levels in heart, placenta and pancreas. Expressed in colonic epithelial cells. Up-regulated in colonic tumors. |
Other Names | [MGC10556; MGC10558; MGC29959; MGC3837; MGC4423; OIP-1; OIP1; OPA interacting protein 1; OPA-interacting protein 1; Thyroid hormone receptor interactor 6; Thyroid receptor interacting protein 6; Thyroid receptor-interacting protein 6; TR-interacting protein 6; TRIP-6; Trip6; TRIP6_HUMAN; TRIP6i2; ZRP 1; ZRP-1; Zyxin-related protein 1] |
Gene, Accession # | [TRIP6], Gene ID: 7205, NCBI: NP_003293.2, UniProt: Q15654 |
Catalog # | MBS9602303 |
Price | $235, $295, $370 |
Order / More Info | TRIP6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |