TRIP6 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTRIP6
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS)
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DescriptionSpecificity: TRIP6 antibody detects endogenous levels of total TRIP6. Description: This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.Function: Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphat
ImmunogenImmunogen: Purified recombinant fragment of human TRIP6 expressed in E. Coli Subcellular Location: Cytoplasm > Cytoskeleton. Cell Junction > Focal Adhesion. Nucleus. Cytoplasm. Shuttles between nucleus and cytoplasm. Tissue Specificity: Abundantly expressed in kidney, liver and lung. Lower levels in heart, placenta and pancreas. Expressed in colonic epithelial cells. Up-regulated in colonic tumors.
Other Names[MGC10556; MGC10558; MGC29959; MGC3837; MGC4423; OIP-1; OIP1; OPA interacting protein 1; OPA-interacting protein 1; Thyroid hormone receptor interactor 6; Thyroid receptor interacting protein 6; Thyroid receptor-interacting protein 6; TR-interacting protein 6; TRIP-6; Trip6; TRIP6_HUMAN; TRIP6i2; ZRP 1; ZRP-1; Zyxin-related protein 1]
Gene, Accession #[TRIP6], Gene ID: 7205, NCBI: NP_003293.2, UniProt: Q15654
Catalog #MBS9602303
Price$235, $295, $370
Order / More InfoTRIP6 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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