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Antigenic Specificity | Band III |
Clone | [Q1/156] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | ELISA (EIA), Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Band 3, also designated AE1, is an erythrocyte membrane glycoprotein that contributes to cell stuctural integrity and mediates exchange of chloride and bicarbonate across the phospholipid bilayer. The diverse functions of the approximately 900 amino acid protein are mediated by two distinct domains. The amino-terminal domain, also known as cdb3 for cytoplasmic domain of erthrocyte membrane band 3, acts as an attachment site for the erythrocyte skeleton by binding ankyrin. The carboxy-terminal, membrane-associated domain carries out exchange transport of anions. Degradation of band 3 can generate an aging antigen known as senescent cell antigen, or SCA, which is expressed on old cells and marks them for removal by the immune sys |
Immunogen | Immunogen: Human fetal liver cells. |
Other Names | [AE1; Anion exchange protein 1; BND3; CD233; DI; Diego blood group; EMPB3; EPB3; Erythrocyte membrane protein band 3; Erythroid anion exchange protein; FR; Froese blood group; RTA1A; SLC4A1; Solute carrier family 4 member 1; SW; Swann blood group; Waldner blood group; WD1; WR; Wright blood group] |
Gene, Accession # | [SLC4A1], Gene ID: 6521, NCBI: NP_000333.1, UniProt: P02730 |
Catalog # | MBS4381253 |
Price | $190, $340, $340 |
Order / More Info | Band III Antibody from MYBIOSOURCE INC. |
Product Specific References | Brock, C.J., Tanner, M.J. and Kempf, C. 1983. Biochem. J. 213: 577-586 |