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Antigenic Specificity | MAPK3 (N-term), 1-30 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkey |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MAPK3. ERK1, a member of the MAP kinase subfamily of Ser/Thr protein kinases, is involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. It phosphorylates EIF4EBP1 and is required for initiation of translation. The protein also phosphorylates microtubule-associated protein-2 (MAP2). ERK1 is activated and tyrosine phosphorylated in response to insulin and NGF. |
Immunogen | n/a |
Other Names | [Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1; MAPK3; ERK1; PRKM3] |
Gene, Accession # | [MAPK3], Gene ID: 5595, NCBI: NP_001035145.1, UniProt: P27361 |
Catalog # | MBS9207957 |
Price | $165, $370 |
Order / More Info | MAPK3 (N-term), 1-30 Antibody from MYBIOSOURCE INC. |
Product Specific References | Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002). Charest, D.L., et al., Mol. Cell. Biol. 13(8):4679-4690 (1993). Owaki, H., et al., Biochem. Biophys. Res. Commun. 182(3):1416-1422 (1992). Gonzalez, F.A., et al., FEBS Lett. 304 (2-3), 170-178 (1992). |