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Antigenic Specificity | APOB48R |
Clone | [2D7] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a,k |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | 0.5mg/ml |
Applications | ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human APOB48R. Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages. |
Immunogen | Immunogen: Partial recombinant corresponding to aa71-170 from human APOB48R with GST tag. MW of the GST tag alone is 26kD. |
Other Names | APOB48R (Apolipoprotein B Receptor, Apolipoprotein B-100 Receptor, Apolipoprotein B-48 Receptor, Apolipoprotein B48 Receptor, apoB-48R, APOBR) |
Gene, Accession # | Gene ID: 55911, NCBI: NP_061160, UniProt: Q0VD83 |
Catalog # | MBS6011388 |
Price | $580 |
Order / More Info | APOB48R Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |