RUSC1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RUSC1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | RUSC1 Antibody: RUSC1, also known as NESCA, shares with the related protein RUSC2 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30% amino acid identity. RUSC1 is an adapter protein that can bind to the TrkA receptor and is necessary in the NGF-induced neurite growth of PC12 cells. RUSC1 has also been shown to interact with IκB kinase- (IKK-) gamma, the regulatory subunit of the IKK complex that is required for NF-κB activation in many signaling pathways such as TNF-R or the TLR pathways. RUSC1 can also bind to the E3 ubiquitin ligase TRAF6, which then catalyzes RUSC1 polyubiquitination. Since overexpression of RUSC1 strongly inhibits TRAF6-mediated polyubiquitination of IKK-gamma, RUSC1 may be |
| Immunogen | Immunogen: RUSC1 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human RUSC1. Buffer: RUSC1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [RUSC1; NESCA; NESCA; RUN and SH3 domain-containing protein 1; New molecule containing SH3 at the carboxy-terminus; Nesca; RUN and SH3 domain containing 1], [RUSC1; RUSC1; NESCA; NESCA; Nesca] |
| Gene, Accession # | [RUSC1], Gene ID: 23623, NCBI: NP_001098673, UniProt: Q9BVN2 |
| Catalog # | MBS151353 |
| Price | $375 |
| Order / More Info | RUSC1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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