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Antigenic Specificity | CMKLR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 2.3mg/ml |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2). |
Immunogen | Immunogen: Synthetic peptide of human CMKLR1 Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3 |
Other Names | [DEZ; RVER1; ChemR23; CHEMERINR] |
Gene, Accession # | [CMKLR1], Gene ID: 1240 |
Catalog # | MBS2543110 |
Price | $110, $150, $225 |
Order / More Info | CMKLR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |