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Antigenic Specificity | AMPK alpha1 |
Clone | [5C9-5B10-6D3] |
Host Species | Mouse |
Reactive Species | human, rat, mouse |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Regulates lipid synthesis by phosphorylating and inactivating lipid metabolic enzymes such as ACACA, A |
Immunogen | Immunogen: Purified recombinant protein expressed in E Coli. |
Other Names | [AAPK1; 5 AMP activated protein kinase alpha 1 catalytic subunit; PRKAA1; SNF1A; MGC33776] |
Gene, Accession # | [PRKAA1], Gene ID: 5562, NCBI: AAH37303.1, UniProt: Q13131 |
Catalog # | MBS8539789 |
Price | $280 |
Order / More Info | AMPK alpha1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |