ADRA1A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityADRA1A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: ADRA1A antibody detects endogenous levels of total ADRA1A. Function: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.Subunit Structure: Homo-and heterooligomer. Heterooligomerizes with ADRA1B homooligomers in cardiac myocytes (PubMed:22120526). Interacts with CAVIN4 (PubMed:24567387).Post-translational Modifications: C-terminal Ser or Thr residues may be phosphorylated.Similarity: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subf
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Cell Membrane Tissue Specificity: Expressed in heart, brain, liver and prostate, but not in kidney, lung, adrenal, aorta and pituitary. Within the prostate, expressed in the apex, base, periurethral and lateral lobe. Isoform 4 is the most abundant isoform expressed in the prostate with high levels also detected in liver and heart. Predicted Cross Reactivity: Rabbit Similarity: Rabbit (89%)
Other Names[ADA1A_HUMAN; ADRA1A; Adra1c; ADRA1L1; Adrenergic alpha1A receptor; Adrenergic alpha1C receptor; Adrenergic receptor alpha 1a; Adrenergic receptor alpha 1c; Adrenergic, alpha 1A, receptor variant 1; Adrenergic, alpha 1A, receptor variant 11; Adrenergic, alpha 1A, receptor variant 3; Adrenergic, alpha 1A, receptor variant 5; Adrenergic, alpha 1A, receptor variant 8; Adrenoceptor alpha 1A; Alpha 1A adrenoreceptor; Alpha 1C adrenergic receptor; Alpha-1A adrenergic receptor; Alpha-1A adrenoceptor; Alpha-1A adrenoreceptor; Alpha-1C adrenergic receptor; Alpha-adrenergic receptor 1c; Alpha1A adrenergic receptor; ALPHA1AAR; G protein coupled receptor]
Gene, Accession #[ADRA1A], Gene ID: 148, NCBI: NP_000671.2, UniProt: P35348
Catalog #MBS9604963
Price$240, $280
Order / More InfoADRA1A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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