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Antigenic Specificity | ADRA1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ADRA1A antibody detects endogenous levels of total ADRA1A. Function: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.Subunit Structure: Homo-and heterooligomer. Heterooligomerizes with ADRA1B homooligomers in cardiac myocytes (PubMed:22120526). Interacts with CAVIN4 (PubMed:24567387).Post-translational Modifications: C-terminal Ser or Thr residues may be phosphorylated.Similarity: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subf |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane Tissue Specificity: Expressed in heart, brain, liver and prostate, but not in kidney, lung, adrenal, aorta and pituitary. Within the prostate, expressed in the apex, base, periurethral and lateral lobe. Isoform 4 is the most abundant isoform expressed in the prostate with high levels also detected in liver and heart. Predicted Cross Reactivity: Rabbit Similarity: Rabbit (89%) |
Other Names | [ADA1A_HUMAN; ADRA1A; Adra1c; ADRA1L1; Adrenergic alpha1A receptor; Adrenergic alpha1C receptor; Adrenergic receptor alpha 1a; Adrenergic receptor alpha 1c; Adrenergic, alpha 1A, receptor variant 1; Adrenergic, alpha 1A, receptor variant 11; Adrenergic, alpha 1A, receptor variant 3; Adrenergic, alpha 1A, receptor variant 5; Adrenergic, alpha 1A, receptor variant 8; Adrenoceptor alpha 1A; Alpha 1A adrenoreceptor; Alpha 1C adrenergic receptor; Alpha-1A adrenergic receptor; Alpha-1A adrenoceptor; Alpha-1A adrenoreceptor; Alpha-1C adrenergic receptor; Alpha-adrenergic receptor 1c; Alpha1A adrenergic receptor; ALPHA1AAR; G protein coupled receptor] |
Gene, Accession # | [ADRA1A], Gene ID: 148, NCBI: NP_000671.2, UniProt: P35348 |
Catalog # | MBS9604963 |
Price | $240, $280 |
Order / More Info | ADRA1A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |