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Antigenic Specificity | CEP104 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 0.4mg/mL |
Applications | Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a centrosomal protein required for ciliogenesis and for ciliary tip structural integrity. The mammalian protein contains three amino-terminal hydrophobic domains, two glycosylation sites, four cysteine-rich motifs, and two regions with homology to the glutamate receptor ionotropic, NMDA 1 protein. During ciliogenesis, the encoded protein translocates from the distal tips of the centrioles to the tip of the elongating cilium. Knockdown of the protein in human retinal pigment cells results in severe defects in ciliogenesis with structural deformities at the ciliary tips. Allelic variants of this gene are associated with the autosomal-recessive disorder Joubert syndrome, which is characterized by a distinctive mid-hindbrain a |
Immunogen | Immunogen: Synthetic peptide of human CEP104 |
Other Names | [CE104; Centrosomal protein of 104 kDa; Cep104; GlyBP; KIAA0562; LOC246295; RP1-286D6.4] |
Gene, Accession # | [CEP104], Gene ID: 9731, NCBI: BC050721, UniProt: O60308 |
Catalog # | MBS2559683 |
Price | $110, $150, $225 |
Order / More Info | CEP104 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |