Edit |   |
Antigenic Specificity | RAB10 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Ras-related protein Rab-10(RAB10) detection. Tested with WB in Human;Mouse;Rat. Background: Ras-related protein Rab-10 is a protein that in humans is encoded by the RAB10 gene. RAB10 belongs to the RAS superfamily of small GTPases. And RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking. The RAB10 gene is mapped to chromosome 2p23.1-p22.3 by radiation hybrid analysis. It was found that the purified recombinant GAP domain of human AS160 showed GAP activity with RAB2A, RAB8A, RAB10, and RAB14, but not with 14 other RABs. Immunoblot analysis showed that these RABs associated with Glut4-positive vesicles in mouse adipocytes. Thereby, it concl |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human RAB10 (153-185aa AKANINIEKAFLTLAEDILRKTPVKEPNSENVD), identical to the related mouse sequence, and different from the related rat sequence by one amino acid. Ig Type: Rabbit IgG |
Other Names | [Ras-related protein Rab-10; GTP binding protein RAB10; Rab10; RAB10 member RAS oncogene family; RAB10_HUMAN; Ras related GTP binding protein; Ras related GTP binding protein RAB10; Ras-related protein Rab-10; RAB10, member RAS oncogene family], [RAB10; RAB10] |
Gene, Accession # | [RAB10], Gene ID: 10890, NCBI: NP_057215.3, UniProt: P61026 |
Catalog # | MBS178168 |
Price | $280 |
Order / More Info | RAB10 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: RAB10 RAB10, member RAS oncogene family. 2. Chen YT, Holcomb C, Moore HP (Aug 1993). Expression and localization of two low molecular weight GTP-binding proteins, Rab8 and Rab10, by epitope tag. Proc Natl Acad Sci U S A 90 (14): 6508-12. 3. He, H., Dai, F., Yu, L., She, X., Zhao, Y., Jiang, J., Chen, X., Zhao, S. Identification and characterization of nine novel human small GTPases showing variable expressions in liver cancer tissues. Gene Expr. 10: 231-242, 2002. |