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Antigenic Specificity | a1-Antitrypsin (AAT, alpha-1-AT, alpha1 Proteinase Inhibitor, alpha1 PI) |
Clone | [1.B.15] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | Protein A purified |
Size | 1 mg |
Concentration | 2.76mg/ml |
Applications | ELISA (EL/EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human Alpha-1-Antitrypsin (AAT). No crossreactivity with alpha-1-acid glycoprotein, serum albumin or other serum proteins. Alpha-1-antitrypsin (AAT) consisting of a single polypeptide chain and has a molecular weight of 51kD. It exists in a number of genetic variants. MM variant is the most common. AAT is synthesized in the liver and it acts as an inhibitor of proteases such as trypsin, elastase, chymotrypsin, collagenase, leukocytic proteases, plasmin and thrombin, which may be released during inflammatory reactions in the lung. In the absence of AAT, these enzymes are not inhibited and they may digest pulmonary parenchyma. AAT deficiency is associated with chronic obstructive lung disease (emphysema) and less frequently with he |
Immunogen | Immunogen: Purified human Alpha-1-Antitrypsin (AAT) |
Other Names | [-a1-Antitrypsin (AAT, alpha-1-AT, alpha1 Proteinase Inhibitor, alpha1 PI)], [SERPINA1; SERPINA1; PI; A1A; AAT; PI1; A1AT; PRO2275; alpha1AT; AAT; PI; SPAAT] |
Gene, Accession # | Gene ID: 5265, NCBI: NP_001121179.1, UniProt: P01009 |
Catalog # | MBS602022 |
Price | $610 |
Order / More Info | a1-Antitrypsin (AAT, alpha-1-AT, alpha1 Proteinase Inhibitor, alpha1 PI) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |