Phospho-AMPK alpha (T172) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-AMPK alpha (T172)
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg, 0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionCatalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Regulates lipid synthesis by phosphorylating and inactivating lipid metabolic enzymes such as ACACA, A
ImmunogenImmunogen: A synthesized peptide derived from human AMPK alpha Subcellular Localization: Cytoplasm. Nucleus. In response to stress, recruited by p53/TP53 to specific promoters.
Other Names[5'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK subunit alpha-2; 2.7.11.1; Acetyl-CoA carboxylase kinase; ACACA kinase; 2.7.11.27; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; 2.7.11.31; PRKAA2; AMPK; AMPK2]
Gene, Accession #[AMPK alpha], Gene ID: 5563, NCBI: NP_006243.2, UniProt: P54646
Catalog #MBS1750261
Price$160, $340, $340
Order / More InfoPhospho-AMPK alpha (T172) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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