Edit |   |
---|---|
Antigenic Specificity | RORalpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RORalpha Polyclonal Antibody detects endogenous levels of RORalpha protein. Nuclear receptor ROR-alpha encoded by RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human RORalpha at AA range: 20-100 |
Other Names | [Rabbit RORalpha; RORA; NR1F1; RZRA; Nuclear receptor ROR-alpha; Nuclear receptor RZR-alpha; Nuclear receptor subfamily 1 group F member 1; Retinoid-related orphan receptor-alpha] |
Gene, Accession # | [RORalpha], Gene ID: 6095, NCBI: NP_002934.1, UniProt: P35398 |
Catalog # | MBS9703066 |
Price | $130, $220, $325 |
Order / More Info | RORalpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |