NGEF - C-terminal region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NGEF - C-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension. |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of mouse NGEF |
| Other Names | [ephexin-1 isoform 1; Ephexin-1; ephexin-1; neuronal guanine nucleotide exchange factor; Eph-interacting exchange protein; Neuronal guanine nucleotide exchange factor] |
| Gene, Accession # | [NGEF], Gene ID: 53972, NCBI: NP_001104784.1, UniProt: Q8CHT1 |
| Catalog # | MBS3223753 |
| Price | $335 |
| Order / More Info | NGEF - C-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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