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Antigenic Specificity | NALP10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1b, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1b processing, and ASC aggregation. NALP10 is thus a potent regulator of apoptosis and inflammation. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 14 amino acid peptide near the amino terminus of human NALP10. |
Other Names | [NACHT, LRR and PYD domains-containing protein 10, NLRP10, NOD8, CLR11.1, PAN5, PYNOD] |
Gene, Accession # | [NALP10], Gene ID: 338322, NCBI: NP_789791 |
Catalog # | MBS9413232 |
Price | $320 |
Order / More Info | NALP10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |