Survivin Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Survivin |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene. Survivin is a member of the inhibitor of apoptosis (IAP) family. The survivin protein functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. Survivin expression is also highly regulated by the cell cycle and is only expressed in the G2-M phase. It is known that Survivin localizes to the mitotic spindle by interaction with tubulin during mitosis and may play a contributing role in regulating mitosis. It also is a direct target gene of the Wnt pathway and is upregulated by beta-catenin. |
| Immunogen | Source Note: This monoclonal antibody is produced by immunizing animals with a polypeptide corresponding to Survivin protein. |
| Other Names | [Apoptosis inhibitor 4; Apoptosis inhibitor survivin; API4; IAP4; Baculoviral IAP repeat-containing protein 5], [BIRC5; BIRC5; API4; EPR-1; API4; IAP4] |
| Gene, Accession # | Gene ID: 332, NCBI: NP_001012270.1, UniProt: O15392 |
| Catalog # | MBS435288 |
| Price | $350, $565 |
| Order / More Info | Survivin Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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