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Antigenic Specificity | TORC1 (MECT1) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels of TORC1(N-terminus) and does not cross-react with related proteins. Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 ?Ser-133? phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). In th |
Immunogen | Immunogen: Purified recombinant human TORC1(N-terminus) protein fragments expressed in E Coli. Cellular Localization: Cytoplasm; Nucleus |
Other Names | [KIAA0616; CREB regulated transcription coactivator 1; CREB-regulated transcription coactivator 1; CRTC1; CRTC1_HUMAN; FLJ14027; KIAA0616; MECT 1; Mucoepidermoid carcinoma translocated 1; Mucoepidermoid carcinoma translocated protein 1; TORC-1; TORC1; Transducer of CREB protein 1; Transducer of regulated cAMP response element binding protein 1; Transducer of regulated cAMP response element-binding protein (CREB) 1; Transducer of regulated cAMP response element-binding protein 1; WAMTP1], [MECT1; TORC1; WAMTP1] |
Gene, Accession # | [TORC1], Gene ID: 23373, NCBI: NP_001091952.1, UniProt: Q6UUV9 |
Catalog # | MBS857757 |
Price | $300 |
Order / More Info | TORC1 (MECT1) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |