Phospho-MYC (T58) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-MYC (T58)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: Xenopus, zebrafish, chicken, mouse, rat, bovine, porcine)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.47
ApplicationsDot Blot (DB), ELISA (EIA), Western Blot (WB)
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DescriptionThis MYC Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T58 of human MYC. MYC participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.
Immunogenn/a
Other Names[Myc proto-oncogene protein; Class E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64; MYC; BHLHE39]
Gene, Accession #[MYC], Gene ID: 4609, NCBI: NP_002458.2, UniProt: P01106
Catalog #MBS9214020
Price$165, $370
Order / More InfoPhospho-MYC (T58) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesQi, Y., et al., Nature 431(7009):712-717 (2004). Wilda, M., et al., Genes Chromosomes Cancer 41(2):178-182 (2004). Dom, et al., Oncogene 23(44):7378-7390 (2004). Pap, T., et al., Arthritis Rheum. 50(9):2794-2802 (2004). Ozawa, N., et al., Endocrinology 145(9):4244-4250 (2004).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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