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Antigenic Specificity | Phospho-MYC (T58) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: Xenopus, zebrafish, chicken, mouse, rat, bovine, porcine) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.47 |
Applications | Dot Blot (DB), ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MYC Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T58 of human MYC. MYC participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia. |
Immunogen | n/a |
Other Names | [Myc proto-oncogene protein; Class E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64; MYC; BHLHE39] |
Gene, Accession # | [MYC], Gene ID: 4609, NCBI: NP_002458.2, UniProt: P01106 |
Catalog # | MBS9214020 |
Price | $165, $370 |
Order / More Info | Phospho-MYC (T58) Antibody from MYBIOSOURCE INC. |
Product Specific References | Qi, Y., et al., Nature 431(7009):712-717 (2004). Wilda, M., et al., Genes Chromosomes Cancer 41(2):178-182 (2004). Dom, et al., Oncogene 23(44):7378-7390 (2004). Pap, T., et al., Arthritis Rheum. 50(9):2794-2802 (2004). Ozawa, N., et al., Endocrinology 145(9):4244-4250 (2004). |