Copper Transporting ATPase 1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Copper Transporting ATPase 1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Copper Transporting ATPase 1 |
| Clone | [S60-4] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG2b |
| Format | APC-Cy7 conjugate |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~180 kDa in rat brain membrane preparations. The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from the cell. ATP7A (also known as Copper-transporting ATPase 1) functions as a transmembrane copper-trans locating P-type ATPase and plays a vital role in systemic copper absorption in the gut and copper reabsorption in the kidney. Polarized epithelial cells such as Madin-Darby canine kidney cells are a physiologically relevant model for systemic copper absorption and reabsorption in vivo. Although ATP7A is not detectable in most normal tissues, it is expressed in a considerable fraction of many common tumor types. Increased expression of ATP7A renders cells resi |
| Immunogen | Immunogen: Synthetic peptide amino acids 42-61 (cytoplasmic C-terminus) of human Copper-transporting ATPase1 |
| Other Names | [Mouse Human Copper Transporting ATPase 1 IgG2b; Copper Transporting ATPase 1 : APC/Cy7; ATP7A; ATP 7A; ATPase Cu transporting; DSMAX; FLJ17790; MC1; MC 1; MK; MNK; OHS; Copper pump 1; Menke; OTTHUMP00000062077; SMAX3; ATPase copper transporting alpha polypeptide; ATPase Cu++ transporting alpha polypeptide (Menkes syndrome); Copper transporting ATPase 1; Cu++ transporting P type ATPase; Menkes disease associated protein; Menkes syndrome] |
| Gene, Accession # | [ATP7A], Gene ID: 538, NCBI: NP_000043.3, UniProt: Q04656 |
| Catalog # | MBS8003082 |
| Price | $510 |
| Order / More Info | Copper Transporting ATPase 1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Samimi G., et al. (2003) Clin. Cancer Res. 9: 5853-9. 2. Samimi G., et al. (2004) Mol Pharmacol. 66: 25-32. 3. Greenough M., et al. (2004) Am. J. Physiol. Cell Physiol. 287: C1463-71. 4. Song, I.S., et al. (2004) Mol. Cancer Ther. 3: 1543-1549. 5. van Dongen, E.M., et al. (2004) Biochem. Biophys. Res. Commun. 323: 789-795. 6. Samimi, G., et al. (2004) Mol Pharmacol 66: 25-32. 7. Morgan, C.T., et al. (2004) J. Biol. Chem. 279: 36363-36371. 8. Barnes, N., et al. (2005) J. Biol. Chem. [Epub]. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies