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Antigenic Specificity | ITGA6 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ITGA6 |
Other Names | [integrin alpha-6 isoform b preproprotein; Integrin alpha-6; integrin alpha-6; integrin subunit alpha 6; CD49 antigen-like family member F; VLA-6] |
Gene, Accession # | [ITGA6], Gene ID: 3655, NCBI: NP_000201.2, UniProt: P23229 |
Catalog # | MBS3221459 |
Price | $335 |
Order / More Info | ITGA6 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |