CD123, IL-3Ra Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD123, IL-3Ra
Clone[CD123-D3]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1/k
Formatunconjugated
Size5 Control Slides, 0.1 mL (Concentrate), 3 ml (Prediluted)
Concentrationn/a
Applicationsn/a
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DescriptionCD123 is alpha chain of the IL-3 receptor. This 60-70 kDa transmembrane protein, by itself, binds to IL-3 with rather low affinity. However, when associated with CD131 (common beta chain), the protein binds to IL-3 with high affinity. The gene coding for the receptor is located in the pseudoautosomal region of the X and Y chromosomes. The receptor belongs to the Type I cytokine-receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. The CD123 receptor, found on pluripotent progenitor cells, induces tyrosine phosphorylation within the cell and promotes proliferation and differentiation within the hematopoietic cell lines. CD123 is expressed by myeloid precursors, macrophages, den
Immunogenn/a
Other Namesn/a
Gene, Accession #[CD123]
Catalog #MBS370017
Price$130, $195, $225
Order / More InfoCD123, IL-3Ra Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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