Edit |   |
Antigenic Specificity | Phospho-PLCG1 (Tyr472) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, zebrafish, bovine, horse, sheep, rabbit, dog, chicken |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-PLCG1 (Tyr472) Antibody detects endogenous levels of PLCG1 only when phosphorylated at Tyr472. Description: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.Post Translational Modifications: Tyrosine phosphorylated in response to signaling via activated FLT3, KIT and PDGFRA (By similarity). Tyrosine phosphorylated by activated FGFR1, FGFR2, FGFR3 and FGFR4. Tyrosi |
Immunogen | Immunogen: A synthesized peptide derived from human PLCG1 around the phosphorylation site of Tyr472. |
Other Names | [1 phosphatidyl D myo inositol 4 5 bisphosphate; 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; Inositoltrisphosphohydrolase; Monophosphatidylinositol phosphodiesterase; NCKAP3; Phosphatidylinositol phospholipase C; Phosphoinositidase C; Phosphoinositide phospholipase C; Phosphoinositide phospholipase C-gamma-1; Phospholipase C 148; Phospholipase C gamma 1; Phospholipase C-gamma-1; Phospholipase C-II; PLC gamma 1; PLC II; PLC-148; PLC-gamma-1; PLC-II; PLC1; PLC148; Plcg1; PLCG1_HUMAN; PLCgamma1] |
Gene, Accession # | [PLCG1], Gene ID: 5335, NCBI: NP_002651.2, UniProt: P19174 |
Catalog # | MBS9610616 |
Price | $225, $280, $340 |
Order / More Info | Phospho-PLCG1 (Tyr472) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |