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Antigenic Specificity | ZBTB17 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ZBTB17 antibody detects endogenous levels of total ZBTB17. Function: Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression. Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Required for early embryonic development during gastrulation. Represses RB1 transcription; this repression can be blocked by interaction with ZBTB49 isoform 3/ZNF509S1 (PubMed:25245 |
Immunogen | Immunogen: A synthesized peptide derived from human ZBTB17 Subcellular Location: Nucleus. Tissue Specificity: Expressed in germinal center B-cells. Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Rabbit (100%), Dog (100%) |
Other Names | [Miz-1; Myc-interacting zinc finger protein 1; Myc-interacting zinc finger protein; ZBT17; ZBT17_HUMAN; Zbtb17; Zinc finger and BTB domain containing protein 17; Zinc finger and BTB domain-containing protein 17; Zinc finger protein 151; Zinc finger protein 60; ZNF151; ZNF60] |
Gene, Accession # | [ZBTB17], Gene ID: 7709, NCBI: NP_001229813.1, UniProt: Q13105 |
Catalog # | MBS9609139 |
Price | $240, $280 |
Order / More Info | ZBTB17 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |