TLR4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTLR4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration0.66-0.8 ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionAffinity Purified Toll-like receptor 4 Antibody. Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+.
ImmunogenImmunogen: Synthetic peptide taken within amino acid region 970-1000 on human TLR4 protein. Expression: Highly expressed in placenta, spleen and peripheral blood leukocytes. Detected in monocytes, macrophages, dendritic cells and several types of T-cells.
Other Names[ARMD10; CD284; Homolog of Drosophila toll; hToll; TLR 4; Toll (Drosophila) homolog; TOLL; Toll Endotoxin Hyporesponsiveness; Toll like receptor 4], [TLR4; TLR4; TOLL; CD284; TLR-4; ARMD10]
Gene, Accession #[TLR4], Gene ID: 7099, NCBI: AAF05316.1, UniProt: O00206
Catalog #MBS540468
Price$390
Order / More InfoTLR4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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