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Antigenic Specificity | Semaphorin-3F (a.a. 746-762) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects a 95 kDa* protein corresponding to the apparent molecular mass of Sema-3F on SDS-PAGE immunoblots of adult mouse brain and liver. One family of inhibitory axon guidance molecules is the semaphorins. The semaphorins include secreted, transmembrane, and GPI-anchored extracellular molecules that have been implicated in neuron development, vascular disease, and tumor progression. There are eight classes of semaphorin genes, all of which are characterized by a conserved 500 amino acid, cystine-rich Sema domain. Semaphorin 3F (Sema-3F) is a class III secreted semaphorin that binds with high affinity to Neuropilin-2, and low affinity to Neuropilin-1. During peripheral and central nervous system development, Sema-3F has critica |
Immunogen | Immunogen: Semaphorin 3F synthetic peptide (coupled to carrier protein) corresponds to amino acids 746 to 762 in human Sema-3F. This sequence is highly conserved in rat and mouse Sema-3F, and has low homology to other semaphorin family members. |
Other Names | [SemaphorinIV; SemaIV; SemaIII/F], [SEMA3F; SEMA3F; SEMA4; SEMAK; SEMA-IV; Sema IV] |
Gene, Accession # | Gene ID: 6405, NCBI: NP_004177.3, UniProt: Q13275 |
Catalog # | MBS474142 |
Price | $325 |
Order / More Info | Semaphorin-3F (a.a. 746-762) Antibody from MYBIOSOURCE INC. |
Product Specific References | Xiang, R.H. (1996) Genomics. 32(1):39.Kolk, S.M. et al. (2009) J Neurosci. 29(40):12542.Tran, T.S. et al. (2009) Nature. 462(7276):1065. |