DFFA Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDFFA
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein A purified
Size0.1 mL
Concentration100ug/100ul
ApplicationsPeptide ELISA (EIA), Western Blot (WB)
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DescriptionSpecificity: DFFA antibody detects endogenous levels of DFFA protein. Not tested with other proteins. Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromat
ImmunogenImmunogen: Synthetic peptide conjugated to KLH
Other Names[DNA fragmentation factor subunit alpha isoform 2; DNA fragmentation factor subunit alpha; DNA fragmentation factor subunit alpha; DFF45; DNA fragmentation factor 45 kDa subunit; inhibitor of CAD; DNA fragmentation factor, 45kDa, alpha polypeptide; DNA fragmentation factor 45 kDa subunit; DFF-45; Inhibitor of CAD; ICAD], [DFFA; DFFA; DFF1; ICAD; DFF-45]
Gene, Accession #[DFFA], Gene ID: 1676, NCBI: NP_998731.1
Catalog #MBS416354
Price$230
Order / More InfoDFFA Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLiu,X., Zou,H., Slaughter,C et,al DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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