ITGAV Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | ITGAV |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Integrins are alpha/beta heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival (1, 2). The integrin family contains at least 18 alpha and 8 beta subunits that form 24 known integrins with distinct tissue distribution and overlaping ligand specificities (3). Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with extracellular environment (inside-out signaling) (1, 2).Several alphaV subfamily members, including alphaVbeta3, alphaVbeta5, alphaVbeta1, are highly expressed in active endothelial cells and cancer cells (3-6) where they play a critical |
| Immunogen | Immunogen: A synthetic peptide of human ITGAV Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [CD51; MSK8; VNRA; VTNR] |
| Gene, Accession # | [ITGAV], Gene ID: 3685, NCBI: NP_001138471.1, UniProt: P06756 |
| Catalog # | MBS8500812 |
| Price | $310 |
| Order / More Info | ITGAV Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Liu, S. et al. (2000) J Cell Sci 113 (Pt 20), 3563-71. 2. Hood, J.D. and Cheresh, D.A. (2002) Nat Rev Cancer 2, 91-100. 3. Koistinen, P. et al. (2004) Int J Cancer 112, 61-70. 4. Davidson, B. et al. (2003) Gynecol Oncol 90, 248-57. 5. Schwartz, E.A. et al. (1999) Circ Res 84, 315-22. 6. Suzuma, K. et al. (1998) Invest Ophthalmol Vis Sci 39, 1028-35. 7. Eliceiri, B.P. and Cheresh, D.A. (1999) J Clin Invest 103, 1227-30. 8. Friedlander, M. et al. (1995) Science 270, 1500-2. 9. Perruzzi, C.A. et al. (2003) J Invest Dermatol 120, 1100-9. 10. Strieth, S. et al. (2006) Int J Cancer 119, 423-31. 11. Kumar, C.C. (2003) Curr Drug Targets 4, 123-31. 12. Tucker, G.C. (2006) Curr Oncol Rep 8, 96-103. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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