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Antigenic Specificity | Human CTLA-4 |
Clone | [A3.4H2.H12] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2ak |
Format | fluorescein (FITC) conjugate |
Size | 0.1 mg |
Concentration | Antibody concentration: 0.1 mg/ml |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human CTLA-4 (CD152). Human CTLA-4 (also known as Cytotoxic T lymphocyte-associated antigen-4, CD152) is a structural homologue of T cell co-stimulatory receptor CD28. CTLA-4 binds to the same ligands (CD80 and CD86) as CD28 but with much higher avidity. It is expressed at very low levels on the cell surface of activated T cells, and is found primarily in the post-Golgi or endosomal compartments of the cell. There is a high degree of overall homology between human and mouse CTLA-4 (>70%), and the cytoplasmic domains of the human, mouse and rabbit sequences are completely conserved. CD152 antibodies have shown both stimulatory and negative regulatory roles in functional experiments. This antibody is suitable for use in Intracell |
Immunogen | Immunogen: Activated T cells. Donor: Balb/c mouse. Fusion Partner:. SP 2/0 myeloma |
Other Names | [CTLA-4, FITC, (clone: A3.4H2.H12), (mouse IgG2ak); FITC Human CTLA-4 (CD152)], [CTLA4; CTLA4; CD; GSE; GRD4; CD152; CTLA-4; IDDM12; CELIAC3; CD152; CTLA-4] |
Gene, Accession # | [CTLA-4], Gene ID: 1493, NCBI: NP_005205.2, UniProt: P16410 |
Catalog # | MBS520258 |
Price | $290 |
Order / More Info | Human CTLA-4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |