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Antigenic Specificity | SRD5A2 (Center), 153-182 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SRD5A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-182 amino acids from the Central region of human SRD5A2. This gene encodes a microsomal protein expressed at highlevels in androgen-sensitive tissues such as the prostate. Theencoded protein is active at acidic pH and is sensitive to the4-azasteroid inhibitor finasteride. Deficiencies in this gene canresult in male pseudohermaphroditism, specifically pseudovaginalperineoscrotal hypospadias (PPSH). |
Immunogen | n/a |
Other Names | [3-oxo-5-alpha-steroid 4-dehydrogenase 2; 5 alpha-SR2; SR type 2; Steroid 5-alpha-reductase 2; S5AR 2; Type II 5-alpha reductase; SRD5A2] |
Gene, Accession # | [SRD5A2], Gene ID: 6716, NCBI: NP_000339.2, UniProt: P31213 |
Catalog # | MBS9201430 |
Price | $165, $370 |
Order / More Info | SRD5A2 (Center), 153-182 Antibody from MYBIOSOURCE INC. |
Product Specific References | Thigpen, A.E., et al. N. Engl. J. Med. 327(17):1216-1219(1992) Thigpen, A.E., et al. J. Clin. Invest. 90(3):799-809(1992) Labrie, F., et al. Endocrinology 131(3):1571-1573(1992) Andersson, S., et al. Nature 354(6349):159-161(1991) |