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Antigenic Specificity | DOT1L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of DOT1L protein. DOT1L encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. DOT1L (DOT1 Like Histone Lysine Methyltransferase) is a Protein Coding gene. Diseases associated with DOT1L include Diffuse Gastric Cancer and Leukemia, Acute Myeloid. Among its related pathways are Chromatin organization and Transcriptional misregulation in cancer. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human DOT1L protein at amino acid sequence of 700-780 |
Other Names | [Rabbit DOT1L; Histone-lysine N-methyltransferase, H3 lysine-79 specific; DOT1-like protein; Histone H3-K79 methyltransferase; H3-K79-HMTase; Lysine N-methyltransferase 4] |
Gene, Accession # | [DOT1L], Gene ID: 84444, NCBI: NP_115871.1, UniProt: Q8TEK3 |
Catalog # | MBS9708989 |
Price | $130, $220, $325 |
Order / More Info | DOT1L Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |