DOT1L Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDOT1L
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThe antibody detects endogenous levels of DOT1L protein. DOT1L encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. DOT1L (DOT1 Like Histone Lysine Methyltransferase) is a Protein Coding gene. Diseases associated with DOT1L include Diffuse Gastric Cancer and Leukemia, Acute Myeloid. Among its related pathways are Chromatin organization and Transcriptional misregulation in cancer.
ImmunogenImmunogen: Synthesized peptide derived from part region of human DOT1L protein at amino acid sequence of 700-780
Other Names[Rabbit DOT1L; Histone-lysine N-methyltransferase, H3 lysine-79 specific; DOT1-like protein; Histone H3-K79 methyltransferase; H3-K79-HMTase; Lysine N-methyltransferase 4]
Gene, Accession #[DOT1L], Gene ID: 84444, NCBI: NP_115871.1, UniProt: Q8TEK3
Catalog #MBS9708989
Price$130, $220, $325
Order / More InfoDOT1L Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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