PPP2R2A Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PPP2R2A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Protein phosphatase 2A subunit B isoform R2-alpha (PPP2R2A) is the component of regulatory subunit B of serine/threonine protein phosphatase 2A (PP2A). PPP2R2A belongs to the R2/B55/PR55 family of regulatory subunit B (1). Evidence suggests that subunit PPP2R2A enhances TGF-beta, Activin, and Nodal signaling pathways (7) and may play an important role in cell cycle regulation (2-4). PPP2R2A/PP2A, B55-alpha/PR55-alpha isoform interacts with the type I TGF-beta receptors via unique WD-40 repeats (5) that contribute to the anti-proliferative function of TGF-beta receptors (6). |
| Immunogen | Immunogen: Recombinant protein of human PPP2R2A Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [B55-ALPHA; B55A; FLJ26613; MGC52248; PR52A; PR55A] |
| Gene, Accession # | [PPP2R2A], Gene ID: 5520, NCBI: NP_001171062.1, UniProt: P63151 |
| Catalog # | MBS8502677 |
| Price | $310 |
| Order / More Info | PPP2R2A Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Li, H.H. et al. (2007) EMBO J 26, 402-11. 2. Mayer-Jaekel, R.E. et al. (1993) Cell 72, 621-33. 3. Clarke, P.R. et al. (1993) Mol Biol Cell 4, 397-411. 4. Healy, A.M. et al. (1991) Mol Cell Biol 11, 5767-80. 5. Neer, E.J. et al. (1994) Nature 371, 297-300. 6. Griswold-Prenner, I. et al. (1998) Mol Cell Biol 18, 6595-604. 7. Batut, J. et al. (2008) Development 135, 2927-37. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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