TRIM29 (Lung Squamous Cell Carcinoma Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TRIM29 (Lung Squamous Cell Carcinoma Marker) |
| Clone | [TRIM29/1042] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG2b, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: It recognizes a 66kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A ant |
| Immunogen | Immunogen: Recombinant fragment (126 Amino acid residues between aa 1-200) of human TRIM29 protein |
| Other Names | [Ataxia telangiectasia group D complementing gene (ATDC); Tripartite motif-containing protein 29 (TRIM29);], [TRIM29; TRIM29; ATDC; ATDC] |
| Gene, Accession # | [TRIM29], Gene ID: 23650, NCBI: NP_036233.2, UniProt: Q14134 |
| Catalog # | MBS438746 |
| Price | $190, $340, $340 |
| Order / More Info | TRIM29 (Lung Squamous Cell Carcinoma Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Kosaka Y, et al. Tripartite motif-containing 29 (TRIM29) is a novel marker for lymph node metastasis in gastric cancer. Ann Surg Oncol. 14(9): 2543-9. 2007. Ring BZ, et al. A novel five-antibody immunohistochemical test for sub-classification of lung carcinoma. Mod Pathol. 22(8): 1032-43. 2009 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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