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Antigenic Specificity | BTRC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of Kidney cell line, using BTRC antibody. 2-transducin repeat-containing protein (2-TrCP or FBW1A) is an F-box family protein characterized by the presence of the protein-protein mediating F-box domain first described in cyclin F. F-box proteins act as substrate adaptors that target proteins containing a specific phosphorylated sequence element, referred to as a phosphodegron, to the SCF E3 ubiquitin ligase complex for ubiquitination (1, 2). 2-TrCP targets many important proteins with diverse functions, such as p53, H-Ras, Smad4, IB+/-, 2-catenin, and the cell cycle checkpoint protein claspin, for ubiquitin-mediated degradation (3-5). Research studies have shown that inhibition of 2-TrCP expres |
Immunogen | Immunogen: Recombinant protein of human BTRC |
Other Names | n/a |
Gene, Accession # | [BTRC] |
Catalog # | MBS419753 |
Price | $385 |
Order / More Info | BTRC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |