CD55, Rat Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD55, Rat |
| Clone | RDII-24 |
| Host Species | Mouse |
| Reactive Species | rat |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | F, Flow Cytometry (FC/FACS), FS, Immuno Assay (IA), Immunoprecipitaion (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The monoclonal antibody RDII-24 recognizes complement decay accelerating factor (DAF), also designated as CD55. Cells express on their surface several proteins which protect against complement attack, namely C receptor I (CR1), decay accelerating factor (DAF), membrane cofactor protein (MCP) and CD59. CR1, DAF and MCP regulate the activation pathways of complement by either accelerating decay of the C3 and C5 convertase (CR1, DAF), or acting as cofactors for the serine protease factor I, which cleaves and irreversibly inactivates C3b (CR1, MCP). Rat DAF (CD55) is a 60 kDa transmembrane protein that binds C3b and C4b to inhibit formation and half-life of the C3 convertases. It belongs to the receptors of complement activ |
| Immunogen | Immunogen: NIH-3T3 cells expressing GPI-anchored rat DAF |
| Other Names | [DAF, CD55], [CD55; CD55; CR; TC; DAF; CROM; CR; DAF] |
| Gene, Accession # | [CD55], Gene ID: 1604, NCBI: AAC60633.1 |
| Catalog # | MBS584073 |
| Price | $555 |
| Order / More Info | CD55, Rat Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Spiller, B et al; Efficient generation of monoclonal antibodies against surface-expressed proteins by hyperexpression in rodent cells. J Immunol Methods 1999, 224: 51 2. Spiller, B et al; Tissue distribution of the rat homologue of decay accelerating factor. Immunol 1999, 97: 374 3. Harris, C et al; Coupling complement regulators to immunoglobulin domains generates effective anti-complement reagents with extended half-life in vivo. Clin Exp Immunol 2002, 129: 198 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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