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Antigenic Specificity | Caspase 7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.69 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total Caspase 7 protein. This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq] |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant fragment corresponding to a region within amino acids 1 and 299 of Caspase 7. |
Other Names | [CMH-1; ICE-LAP3; MCH3; CASP7; caspase 7; apoptosis-related cysteine protease ; CASP-7; Lice2 alpha/beta/gamma; caspase 7 isoform delta; apoptotic protease MCH-3; caspase-7 a] |
Gene, Accession # | Gene ID: 840, NCBI: NP_001218.1, UniProt: P55210 |
Catalog # | MBS9414025 |
Price | $320 |
Order / More Info | Caspase 7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |