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Antigenic Specificity | SLC1A3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:7521911, PubMed:8123008, PubMed:20477940, PubMed:26690923, PubMed:28032905, PubMed:28424515). Functions as a symporter that transports one amino acid molecule together with two or three Na+ ions and one proton, in parallel with the counter-transport of one K+ ion (PubMed:20477940). Mediates Cl-flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na+ symport (PubMed:20477940). Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 453-542 of human SLC1A3 (NP 004163.3). |
Other Names | [EA6; EAAT1; GLAST; GLAST1] |
Gene, Accession # | [SLC1A3], Gene ID: 6507, NCBI: NP_001276868.1, UniProt: P43003 |
Catalog # | MBS8550038 |
Price | $280 |
Order / More Info | SLC1A3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |