CD2/Lymphocyte Function Antigen 2 (LFA-2) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD2/Lymphocyte Function Antigen 2 (LFA-2) |
| Clone | [RPA-2.10] |
| Host Species | Mouse |
| Reactive Species | human, chimpanzee, baboon, monkey, porcine |
| Isotype | IgG1, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Functional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells. |
| Immunogen | Immunogen: Recombinant full-length human CD2 protein |
| Other Names | [Erythrocyte receptor; LFA-2; LFA-3 receptor; Ly-37; Lymphocyte function antigen 2; Rosette receptor; SRBC; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5; T11] |
| Gene, Accession # | [CD2/LFA-2], Gene ID: 914, NCBI: NP_001758.2, UniProt: P06729 |
| Catalog # | MBS4381381 |
| Price | $190, $340, $340 |
| Order / More Info | CD2/Lymphocyte Function Antigen 2 (LFA-2) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Perona-Wright G, et al. 2010. Nat. Immunol. 11:520. (FC). 2. Zaretsky AG, et al. 2009. J. Exp Med. 206:991. (IF) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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