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Antigenic Specificity | CMTM4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CMTM4 antibody detects endogenous levels of total CMTM4. Function: Acts as a backup for CMTM6 to regulate plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. May protect PD-L1/CD274 from being polyubiquitinated and targeted for degradation.Subunit Structure: Interacts with PD-L1/CD274 and CMTM6.Similarity: Belongs to the chemokine-like factor family. |
Immunogen | Immunogen: A synthesized peptide derived from human CMTM4 Tissue Specificity: Highly expressed in testis and prostate. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Chicken Similarity: Pig (100%), Zebrafish (100%), Bovine (100%), Chicken (100%) |
Other Names | [Chemokine like factor super family 4; Chemokine-like factor superfamily member 4; CKLF-like MARVEL transmembrane domain containing 4; CKLF4; CKLFSF4; CMTM4] |
Gene, Accession # | [CMTM4], Gene ID: 146223, NCBI: NP_848933.1, UniProt: Q8IZR5 |
Catalog # | MBS9602085 |
Price | $240, $280 |
Order / More Info | CMTM4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |