Edit |   |
---|---|
Antigenic Specificity | Bcl-7a |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Bcl-7a Polyclonal Antibody detects endogenous levels of Bcl-7a protein. BCL7A (BCL tumor suppressor 7A) is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for BCL7A. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human Bcl-7a at AA range: 40-120 |
Other Names | [Rabbit Bcl-7a; BCL7A; B-cell CLL/lymphoma 7 protein family member A] |
Gene, Accession # | [BCL-7a], Gene ID: 605, NCBI: NP_001019979.1, UniProt: Q4VC05 |
Catalog # | MBS9706680 |
Price | $130, $220, $325 |
Order / More Info | Bcl-7a Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |