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Antigenic Specificity | AKR7A2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: AKR7A2 antibody detects endogenous levels of total AKR7A2. Description: The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. [provided by RefSeq, Oct 2011]Function: Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-h |
Immunogen | Immunogen: A synthesized peptide derived from human AKR7A2 Subcellular Location: Golgi Apparatus. Cytoplasm. Tissue Specificity: Detected in brain, liver, small intestine and testis, and at lower levels in heart, prostate, skeletal muscle and spleen. Detected in kidney proximal and distal tubules, endothelial cells lining the Bowman's capsules and some cysts. Detected at low levels in lung and pancreas (at protein level). Widely expressed. Predicted Cross Reactivity: Pig, Bovine, Dog Similarity: |
Other Names | [AFAR; AFAR1; AFB1 aldehyde reductase 1; AFB1 AR1; AFB1-AR 1; AFB1AR1; Aflatoxin aldehyde reductase; Aflatoxin B1 aldehyde reductase member 2; Aflatoxin beta1 aldehyde reductase; Aiar; AKR7; Akr7a2; Aldo keto reductase family 7; Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase; Aldo keto reductase family 7 member A2; Aldo keto reductase family 7, member A2 (aflatoxin aldehyde reductase); Aldoketoreductase 7; ARK72_HUMAN; SSA reductase; Succinic semialdehyde reductase] |
Gene, Accession # | [AKR7A2], Gene ID: 8574, NCBI: NP_003680.2, UniProt: O43488 |
Catalog # | MBS9607017 |
Price | $240, $280 |
Order / More Info | AKR7A2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |