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Antigenic Specificity | MYST2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total MYST2 protein. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.Iizuka M., J. Biol. Chem. 274:23027-23034(1999).Sharma M., J. Biol. Chem. 275:35200-35208(2000).Olsen J.V., Cell 127:635-648(2006). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human MYST2. |
Other Names | [EC 2.3.1.48; HBO1; HBOA; MYST histone acetyltransferase 2] |
Gene, Accession # | [MYST2], Gene ID: 11143, NCBI: NP_001186084.1, UniProt: O95251 |
Catalog # | MBS9401056 |
Price | $200, $255 |
Order / More Info | MYST2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |