IL-23R Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIL-23R
Clone[ABM25G4]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
FormatProtein G purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionIL-23, a member of the IL-12 cytokine family, is composed of a p40 subunit, which is shared with IL-12, and a p19 subunit, with an approximate molecular weight of 60 kDa. IL-23 is produced by activated dendritic cells and macrophages in response to microorganisms. IL-23 promotes Th17 cells producing TNF-a, IL-17, IL-6, IL-22, GM-CSF, and other novel factors, which are associated with the induction of autoimmune inflammation. IL-23 is essential for Th17 differentiation, expansion, and survival by binding to its receptor, thereby activating the signaling pathway. Many studies revealed that the IL-23/Th17 pathway is implicated in the pathophysiology of various autoimmune diseases, such as autoimmune arthritis, primary biliary cirrhosis, and in
ImmunogenAntigen: IL-23R. Immunogen Information: A partial length recombinant protein (a.a 250-450) of IL-23R was used as the immunogen for this antibody. Conjugation: Unconjugated
Other Names[Interleukin-23 receptor; IL-23 receptor; IL-23R], [IL23R]
Gene, Accession #[IL-23R], Gene ID: 149233, NCBI: NP_653302.2, UniProt: Q5VWK5
Catalog #MBS668975
Price$290
Order / More InfoIL-23R Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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