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Antigenic Specificity | SMUG1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine), nor other oxidized bases. The activity is damage-specific and salt-dependent. The substrate preference is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at low salt concentration, and dsDNA (G pair) > d |
Immunogen | Immunogen: Recombinant human Single-strand selective monofunctional uracil DNA glycosylase protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-26878 / sc-26880 / sc-292616 / sc-98849 |
Other Names | [Single-strand selective monofunctional uracil DNA glycosylase (EC:3.2.2.-); SMUG1], [SMUG1; SMUG1; FDG; UNG3; HMUDG] |
Gene, Accession # | [SMUG1], Gene ID: 23583, NCBI: NP_001230716.1, UniProt: Q53HV7 |
Catalog # | MBS1493294 |
Price | $160, $235 |
Order / More Info | SMUG1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |