CHRNA10 (Center), 179-206 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCHRNA10 (Center), 179-206
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: rat)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
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DescriptionThis CHRNA10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-206 amino acids from the Central region of human CHRNA10. CHRNA10 is an ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hea
Immunogenn/a
Other Names[Neuronal acetylcholine receptor subunit alpha-10; Nicotinic acetylcholine receptor subunit alpha-10; NACHR alpha-10; CHRNA10; NACHRA10]
Gene, Accession #[CHRNA10], Gene ID: 57053, NCBI: NP_065135.2, UniProt: Q9GZZ6
Catalog #MBS9211273
Price$165, $370
Order / More InfoCHRNA10 (Center), 179-206 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSaccone, N.L., et al. Genes Brain Behav. 9(7):741-750(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Rigbi, A., et al. Pharmacogenomics J. (2010) In press : Need, A.C., et al. Eur. J. Hum. Genet. 17(7):946-957(2009) Saccone, N.L., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (4), 453-466 (2009) :
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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