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Antigenic Specificity | CHRNA10 (Center), 179-206 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CHRNA10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-206 amino acids from the Central region of human CHRNA10. CHRNA10 is an ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hea |
Immunogen | n/a |
Other Names | [Neuronal acetylcholine receptor subunit alpha-10; Nicotinic acetylcholine receptor subunit alpha-10; NACHR alpha-10; CHRNA10; NACHRA10] |
Gene, Accession # | [CHRNA10], Gene ID: 57053, NCBI: NP_065135.2, UniProt: Q9GZZ6 |
Catalog # | MBS9211273 |
Price | $165, $370 |
Order / More Info | CHRNA10 (Center), 179-206 Antibody from MYBIOSOURCE INC. |
Product Specific References | Saccone, N.L., et al. Genes Brain Behav. 9(7):741-750(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Rigbi, A., et al. Pharmacogenomics J. (2010) In press : Need, A.C., et al. Eur. J. Hum. Genet. 17(7):946-957(2009) Saccone, N.L., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (4), 453-466 (2009) : |